{"schema":"sb.node.v1","id":"sb:e/ef26b299761c540bfb33635a","kind":"entity","label":{"text":"cber","locale":"en"},"identity":{"anchor":"label:en:cber","strength":"label"},"asOf":{"knowledgeCutoff":"2026-10-10T23:27:45.667496+00:00","snapshot":"deploy 2e5ddc12e7da6a156749e183c3b335c8968e59b7"},"lens":{"kind":"public"},"build":{"plane":"projected","builtFrom":["entity_graph.slim.json","entity_receipts (deploy asset)","event_graph.json","truth_records (deploy asset)","corroborated_record.json"],"rule":"node-projection.entity@v1"},"standing":{"evidence":{"supporting":36,"separatePublishers":4,"basis":"documents that mention the subject and the outlets that carried them; a mention is evidence the referent is in use, not evidence about any claim","receiptsOnTopic":{"state":"partial","share":0.194,"named":7,"of":36,"basis":"documents whose own title or summary lead names the subject, over every counted document that mentions it anywhere (the entity graph's measurement); receipts are drawn from the former only","blind":["only 19% of the 36 documents measured name the subject in their own text; the rest mention it in passing, so standing.evidence.supporting overstates coverage about it"]}},"admission":{"state":"canonical","reason":"entity graph provenance 'curated'; the node carries no promotion receipt in v1","policy":"EQ-PROMOTION (receipt not carried)"},"disposition":{"state":"served","reason":"public record"},"validity":{"from":"2026-04-14","to":"2026-10-09","basis":"first and last day we saw it mentioned; not the subject's own lifetime"},"measurement":{"state":"partial","blind":["assertion coverage 0.417: about 58% of mentions carry no typed assertion"]}},"dimensions":{"domains":["biotech_pharma","pharma-regulatory"],"activeDays":23,"assertions":{"regulatory-approval":14,"award":1}},"up":[],"upNote":"An entity is a root: it is contained by nothing. Pan out by following R.","children":{"count":7,"byKind":{"observation":7},"items":[{"id":"sb:o/abdc13ee553c467883e34d0d","kind":"observation","label":"FDA · 2026-09-30 · Study Data Standards Resources","url":"http://www.fda.gov/industry/fda-data-standards-advisory-board/study-data-standards-resources"},{"id":"sb:o/262432e16deeb18d59a135df","kind":"observation","label":"FDA · 2026-09-18 · CDER Data Standards Program","url":"http://www.fda.gov/drugs/electronic-regulatory-submission-and-review/cder-data-standards-program"},{"id":"sb:o/d6ef7e1eb3a2cb6e84ab6db3","kind":"observation","label":"FDA · 2026-09-17 · Recently Issued Guidance Documents","url":"http://www.fda.gov/vaccines-blood-biologics/biologics-guidances/recently-issued-guidance-documents"},{"id":"sb:o/b0fcc4fbe96394ed2303eca9","kind":"observation","label":"FDA · 2026-09-11 · FDA Rare Disease Innovation Hub","url":"http://www.fda.gov/industry/medical-products-rare-diseases-and-conditions/fda-rare-disease-innovation-hub"},{"id":"sb:o/7c3bb02687cf97410ce5912c","kind":"observation","label":"STAT News · 2026-09-10 · STAT+: Orexin discoverers awarded prestigious Lasker award","url":"https://www.statnews.com/2026/09/09/biotech-news-orexin-discovers-awawrded-prestigious-lasker-award/?utm_campaign=rss"},{"id":"sb:o/b1b1112392a0cf62fedb2f85","kind":"observation","label":"FDA Drug News · 2026-06-13 · [APPROVAL] Real-World Evidence Submissions to the Center for Biologics Evaluation and Research & the Center for Drug Evaluation and Research","url":"http://www.fda.gov/science-research/real-world-evidence/real-world-evidence-submissions-center-biologics-evaluation-and-research-center-drug-evaluation-and"},{"id":"sb:o/be72399582bbc5763521f968","kind":"observation","label":"FDA Drug News · 2026-04-17 · Electronic Submission of Adverse Event Reports to FDA Adverse Event Reporting System (FAERS) using International Council for Harmonisation (ICH) E2B(R3) Standards - 04/04…","url":"http://www.fda.gov/drugs/news-events-human-drugs/electronic-submission-adverse-event-reports-fda-adverse-event-reporting-system-faers-using"}],"cursor":null,"order":"newest first; we keep the 7 newest receipts for this entity whose own title or summary lead (the entity graph's test) names it. Its other observations are counted in standing.evidence.supporting but are not addressable in v1"},"relations":{"count":{"state":"cannot-measure","reason":"claims: this subject's maintained record could not be read (the maintained record \"cber\" could not measure its claims: this subject was retired from the publication registry on 2026-09-20 (no longer clears the admission conditions — re-checked 2026-09-20 (no receipt in the corpus-evidence shard for this label)); the record is kept as a dated tombstone and is no longer maintained). The items listed come from the passes that could be read"},"byKind":{"co-mentioned":10},"items":[{"kind":"relation","label":"co-mentioned with fda (36 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/e06360e0bd440389f71495a2"},{"kind":"relation","label":"co-mentioned with cder (30 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/c16b0211b3750725dc29d7de"},{"kind":"relation","label":"co-mentioned with drug evaluation (21 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/c058aaab4043848a0b70530f"},{"kind":"relation","label":"co-mentioned with biologics evaluation (20 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/261af4582d9f31af36da8937"},{"kind":"relation","label":"co-mentioned with drug development (15 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/064403ff1d1b9447e2a8d71e"},{"kind":"relation","label":"co-mentioned with biological products (13 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/411eb73a79c3992499065dbe"},{"kind":"relation","label":"co-mentioned with drug administration (13 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/4e3fff8f0994b80a0659241f"},{"kind":"relation","label":"co-mentioned with investigational new drug (12 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/3a428f286de70cae438070d3"},{"kind":"relation","label":"co-mentioned with clinical trial (11 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/05f236aadd24350fa40c22de"},{"kind":"relation","label":"co-mentioned with cdrh (9 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/d54d4c8470beb8ec1c3c54ba"}],"cursor":null,"order":"situations first, then claims (the subject's own maintained record, then site-wide corroborated clusters; each label ends with its standing), then co-mentions by shared documents, descending. Co-mentions are the ten strongest the entity graph keeps per entity"},"edge":{"state":"continues"},"links":{"rest":"/api/v1/node/e/ef26b299761c540bfb33635a","mcp":"traverse {\"id\":\"sb:e/ef26b299761c540bfb33635a\"}","page":"/entity/cber/"},"limits":{"levelsPerCall":1,"pageSize":10,"maxPageSize":50,"membersMax":50,"statement":"One level per call: depth is 1 and only 1, and there is no whole-graph dump. pageSize 1-50 (default 10); a page limit is a cursor, never an edge. Members are listed up to 50. At most 60 traverse calls a minute per caller (runaway-loop protection, not a meter). One knowledge cutoff is served: the deploy's."},"actions":[{"verb":"unfold","lit":true,"effect":"read","layer":"cantina","call":"traverse {\"id\":\"sb:e/ef26b299761c540bfb33635a\",\"level\":\"children\"}"},{"verb":"fold","lit":true,"effect":"read","layer":"cantina","call":"traverse {\"id\":\"sb:e/ef26b299761c540bfb33635a\"}"},{"verb":"panOut","lit":false,"effect":"read","layer":"cantina","reason":"An entity is a root: it is contained by nothing. Pan out by following R."},{"verb":"follow","lit":true,"effect":"read","layer":"cantina","call":"traverse {\"id\":\"sb:e/ef26b299761c540bfb33635a\",\"level\":\"relations\"}"},{"verb":"receipts","lit":false,"effect":"read","layer":"cantina","reason":"receipts are the observations below this node; unfold to reach them"},{"verb":"edge","lit":true,"effect":"read","layer":"cantina","call":"traverse {\"id\":\"sb:e/ef26b299761c540bfb33635a\"}"},{"verb":"asOf","lit":false,"effect":"read","layer":"cantina","reason":"v1 serves one knowledge cutoff, this deploy's; walking an earlier cutoff needs retained history (EQ-REPLAY), which v1 does not keep"},{"verb":"switchObserver","lit":false,"effect":"read","layer":"cantina","reason":"the public record is the same for every observer; traversal through a Watch's lens is not served in v1"},{"verb":"readOriginal","lit":false,"effect":"read","layer":"cantina","reason":"no translation is applied on this node; every label is the source's own text"},{"verb":"save","lit":false,"effect":"watch-declaration","layer":"workshop","reason":"saving applies to a configured Watch; configure one around this node first (free), then save it"},{"verb":"deliver","lit":false,"effect":"watch-declaration","layer":"workshop","reason":"delivery applies to a saved Watch"},{"verb":"format","lit":false,"effect":"watch-declaration","layer":"workshop","reason":"output format applies to a saved Watch"},{"verb":"deltaR","lit":false,"effect":"read","layer":"workshop","reason":"Delta R needs a saved Watch with a previous reading"},{"verb":"read","lit":false,"effect":"read","layer":"docking-bay","reason":"one-time Reads are parked until the Commander decides their shape (#938)"}]}