Entity · moving across domains

Colorectal Cancer

Cancer of the colon or rectum — among the most common cancers worldwide and a major focus of screening and drug development.

As of 9 Nov 2026Last evidence 8 Nov 2026

What is happening now

Sotorasib plus panitumumab extends progression-free survival in KRAS G12C-mutant colorectal cancer
Reported claim · first reported 7 Nov 2026 · 1 claim · best-carried claim: 1 separate publisher
Agenus Reports More Than Half of Patients with Refractory MSS Metastatic Colorectal Cancer Achieved Long-Term Survival Following BOT+BAL Treatment at SITC 2026 - BioSpace
Reported claim · first reported 6 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers
Comparative efficacy and safety of second- and later-line BRAF-targeted regimens in BRAF V600E-mutant metastatic colorectal cancer: A systematic review and network meta-analysis.
Reported claim · first reported 6 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers
The role of gut microbiota on the tumor microenvironment in colorectal cancer: a systematic review and meta-analysis.
Reported claim · first reported 4 Nov 2026 · 1 claim · best-carried claim: 1 separate publisher
A tumor transcriptomic atlas across eight decades of life reveals distinct features of early-onset colorectal cancer.
Reported claim · first reported 4 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers

All 8 events and claims involving Colorectal Cancer

What changed

Attention Rising: 65 mentions on 9 Nov 2026, against 47 on 19 Oct 2026 (+38%).
State Last recorded change: coverage state went from rising to steady on 9 Nov 2026 (9 changes recorded since 3 Nov 2026).
Claims No claim first reported since 8 Nov 2026.

How well we know this

2,119 documents · 430 publishers · 6% say something specific about it · last evidence 8 Nov 2026

Gap: 6% of mentions say something specific about it; the rest only name it
Gap: 2 receipts withheld: no source link (the same rule the topic record applies)

In this snapshot’s daily coverage:

Reported alongside Colorectal Cancer

Names most often reported alongside it; bigger circles and heavier lines mean more shared documents. A dashed circle has no page of its own yet.

Immunotherapy · 381 shared documents
KRAS · 195 shared documents
ctDNA · 163 shared documents · no page of its own yet
Overall Survival · 160 shared documents · no page of its own yet
AI · 139 shared documents
FDA · 132 shared documents · no page of its own yet
Lung Cancer · 122 shared documents · no page of its own yet
Braf · 112 shared documents · no page of its own yet
Cancer Cells · 105 shared documents · no page of its own yet
MSI-H · 96 shared documents · no page of its own yet

Story momentum

Rising

The word compares 65 mentions on 9 Nov 2026 with 47 on 19 Oct 2026 (+38%); a change of less than 8% either way reads Steady.

Daily mentions -6% from 25 Sept 2026 to 9 Nov 2026, between 12 and 162 a day

How often tracked coverage mentions Colorectal Cancer, day by day.

Market price, cited

Not priced yet

No open prediction market prices a question materially about Colorectal Cancer yet. Ask about Colorectal Cancer

No market price on file: no prediction market prices a question about this name yet

Coverage volume and market price are separate measures.

On the desk: Health & Bio Desk

For developers

This page is also an object: GET https://sigb.ai/api/v1/node/e/e65e9524bedac8b311cd8e6e returns the same record as sb.node.v1. Or call the get_entity MCP tool at https://sigb.ai/api/mcp with name colorectal cancer.

{
  "name": "colorectal cancer",
  "label": "Colorectal Cancer",
  "asOf": "2026-11-09",
  "mentions": 65,
  "domains": 12,
  "node": {
    "id": "sb:e/e65e9524bedac8b311cd8e6e",
    "schema": "sb.node.v1",
    "rest": "https://sigb.ai/api/v1/node/e/e65e9524bedac8b311cd8e6e",
    "knowledgeCutoff": "2026-11-09T23:25:51.141948+00:00",
    "snapshot": "this deploy's committed data files (commit not exposed in this runtime)"
  },
  "coverageTrend": "rising",
  "history": {
    "since": "2026-11-03T13:08:56.552092+00:00",
    "changes": 9
  },
  "whereFrom": {
    "level": "counts",
    "label": "65 mentions across 12 domains",
    "children": [
      {
        "level": "reports",
        "label": "6 reports drawn on this page, each with its link",
        "children": {
          "count": 6,
          "unfold": "expand=+1"
        }
      },
      {
        "level": "domains",
        "label": "12 coverage domains",
        "children": {
          "count": 12,
          "unfold": "expand=+1"
        }
      },
      {
        "level": "not shown",
        "label": "The other 59 mentions",
        "edge": "counted daily from tracked coverage; single mentions are not listed one by one"
      }
    ]
  }
}

The figures on this page, as data. The tool returns the full entity record.

Events involving Colorectal Cancer

Most-reported first, then newest. Registered events come from the event record; reported events are groups of claims about one occurrence. Claims are grouped when they were first reported within 2 days of each other and either name at least 2 of the same people, places or things besides this one, or share at least 25% of their wording. Each claim keeps its own record.

Sotorasib plus panitumumab extends progression-free survival in KRAS G12C-mutant colorectal cancer
Reported claim · first reported 7 Nov 2026 · 1 claim · best-carried claim: 1 separate publisher
could not check
Agenus Reports More Than Half of Patients with Refractory MSS Metastatic Colorectal Cancer Achieved Long-Term Survival Following BOT+BAL Treatment at SITC 2026 - BioSpace
Reported claim · first reported 6 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers
single source
Comparative efficacy and safety of second- and later-line BRAF-targeted regimens in BRAF V600E-mutant metastatic colorectal cancer: A systematic review and network meta-analysis.
Reported claim · first reported 6 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers
could not check
The role of gut microbiota on the tumor microenvironment in colorectal cancer: a systematic review and meta-analysis.
Reported claim · first reported 4 Nov 2026 · 1 claim · best-carried claim: 1 separate publisher
single source
A tumor transcriptomic atlas across eight decades of life reveals distinct features of early-onset colorectal cancer.
Reported claim · first reported 4 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers
reported by two
IFNAR1 stabilization sustains CD8+ T cell persistence in IFN-high colorectal cancer liver metastases
Reported claim · first reported 4 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers
could not check
Therapy-induced tumour senescence drives oxaliplatin resistance via ADORA1-dependent palmitic acid metabolic reprogramming in colorectal cancer.
Reported claim · first reported 3 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers
could not check
HER3 mediates metabolic reprogramming in metastatic colorectal and pancreatic cancer
Reported claim · first reported 3 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers
could not check

Walk the record from Colorectal Cancer

Open where it comes from, follow a claim or a related name, and use the trail to come back. Every step says what it is, how it stands and when. Machines read the same record.