Entity · moving across domains

Colorectal Cancer

Cancer of the colon or rectum — among the most common cancers worldwide and a major focus of screening and drug development.

As of 9 Nov 2026Last evidence 8 Nov 2026

What is happening now

  • Sotorasib plus panitumumab extends progression-free survival in KRAS G12C-mutant colorectal cancer

    Reported claim · first reported 7 Nov 2026 · 1 claim · best-carried claim: 1 separate publisher

  • Agenus Reports More Than Half of Patients with Refractory MSS Metastatic Colorectal Cancer Achieved Long-Term Survival Following BOT+BAL Treatment at SITC 2026 - BioSpace

    Reported claim · first reported 6 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers

  • Comparative efficacy and safety of second- and later-line BRAF-targeted regimens in BRAF V600E-mutant metastatic colorectal cancer: A systematic review and network meta-analysis.

    Reported claim · first reported 6 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers

  • The role of gut microbiota on the tumor microenvironment in colorectal cancer: a systematic review and meta-analysis.

    Reported claim · first reported 4 Nov 2026 · 1 claim · best-carried claim: 1 separate publisher

  • A tumor transcriptomic atlas across eight decades of life reveals distinct features of early-onset colorectal cancer.

    Reported claim · first reported 4 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers

All 8 events and claims involving Colorectal Cancer

What changed

  • Attention Rising: 65 mentions on 9 Nov 2026, against 47 on 19 Oct 2026 (+38%).
  • State Last recorded change: coverage state went from rising to steady on 9 Nov 2026 (9 changes recorded since 3 Nov 2026).
  • Claims No claim first reported since 8 Nov 2026.

How well we know this

2,119 documents · 430 publishers · 6% say something specific about it · last evidence 8 Nov 2026

  • Gap: 6% of mentions say something specific about it; the rest only name it
  • Gap: 2 receipts withheld: no source link (the same rule the topic record applies)

In this snapshot’s daily coverage:

Reported alongside Colorectal Cancer

Names most often reported alongside it; bigger circles and heavier lines mean more shared documents. A dashed circle has no page of its own yet.

ImmunotherapyKRASAI
  • Immunotherapy · 381 shared documents
  • KRAS · 195 shared documents
  • ctDNA · 163 shared documents · no page of its own yet
  • Overall Survival · 160 shared documents · no page of its own yet
  • AI · 139 shared documents
  • FDA · 132 shared documents · no page of its own yet
  • Lung Cancer · 122 shared documents · no page of its own yet
  • Braf · 112 shared documents · no page of its own yet
  • Cancer Cells · 105 shared documents · no page of its own yet
  • MSI-H · 96 shared documents · no page of its own yet

Story momentum

Rising

The word compares 65 mentions on 9 Nov 2026 with 47 on 19 Oct 2026 (+38%); a change of less than 8% either way reads Steady.

Daily mentions -6% from 25 Sept 2026 to 9 Nov 2026, between 12 and 162 a day

How often tracked coverage mentions Colorectal Cancer, day by day.

Market price, cited

Not priced yet

No open prediction market prices a question materially about Colorectal Cancer yet. Ask about Colorectal Cancer

No market price on file: no prediction market prices a question about this name yet

Coverage volume and market price are separate measures.

On the desk: Health & Bio Desk

For developers

This page is also an object: GET https://sigb.ai/api/v1/node/e/e65e9524bedac8b311cd8e6e returns the same record as sb.node.v1. Or call the get_entity MCP tool at https://sigb.ai/api/mcp with name colorectal cancer.

{
  "name": "colorectal cancer",
  "label": "Colorectal Cancer",
  "asOf": "2026-11-09",
  "mentions": 65,
  "domains": 12,
  "node": {
    "id": "sb:e/e65e9524bedac8b311cd8e6e",
    "schema": "sb.node.v1",
    "rest": "https://sigb.ai/api/v1/node/e/e65e9524bedac8b311cd8e6e",
    "knowledgeCutoff": "2026-11-09T23:25:51.141948+00:00",
    "snapshot": "this deploy's committed data files (commit not exposed in this runtime)"
  },
  "coverageTrend": "rising",
  "history": {
    "since": "2026-11-03T13:08:56.552092+00:00",
    "changes": 9
  },
  "whereFrom": {
    "level": "counts",
    "label": "65 mentions across 12 domains",
    "children": [
      {
        "level": "reports",
        "label": "6 reports drawn on this page, each with its link",
        "children": {
          "count": 6,
          "unfold": "expand=+1"
        }
      },
      {
        "level": "domains",
        "label": "12 coverage domains",
        "children": {
          "count": 12,
          "unfold": "expand=+1"
        }
      },
      {
        "level": "not shown",
        "label": "The other 59 mentions",
        "edge": "counted daily from tracked coverage; single mentions are not listed one by one"
      }
    ]
  }
}

The figures on this page, as data. The tool returns the full entity record.

Events involving Colorectal Cancer

Most-reported first, then newest. Registered events come from the event record; reported events are groups of claims about one occurrence. Claims are grouped when they were first reported within 2 days of each other and either name at least 2 of the same people, places or things besides this one, or share at least 25% of their wording. Each claim keeps its own record.

  • Sotorasib plus panitumumab extends progression-free survival in KRAS G12C-mutant colorectal cancer

    Reported claim · first reported 7 Nov 2026 · 1 claim · best-carried claim: 1 separate publisher

    could not check

  • Agenus Reports More Than Half of Patients with Refractory MSS Metastatic Colorectal Cancer Achieved Long-Term Survival Following BOT+BAL Treatment at SITC 2026 - BioSpace

    Reported claim · first reported 6 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers

    single source

  • Comparative efficacy and safety of second- and later-line BRAF-targeted regimens in BRAF V600E-mutant metastatic colorectal cancer: A systematic review and network meta-analysis.

    Reported claim · first reported 6 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers

    could not check

  • The role of gut microbiota on the tumor microenvironment in colorectal cancer: a systematic review and meta-analysis.

    Reported claim · first reported 4 Nov 2026 · 1 claim · best-carried claim: 1 separate publisher

    single source

  • A tumor transcriptomic atlas across eight decades of life reveals distinct features of early-onset colorectal cancer.

    Reported claim · first reported 4 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers

    reported by two

  • IFNAR1 stabilization sustains CD8+ T cell persistence in IFN-high colorectal cancer liver metastases

    Reported claim · first reported 4 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers

    could not check

  • Therapy-induced tumour senescence drives oxaliplatin resistance via ADORA1-dependent palmitic acid metabolic reprogramming in colorectal cancer.

    Reported claim · first reported 3 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers

    could not check

  • HER3 mediates metabolic reprogramming in metastatic colorectal and pancreatic cancer

    Reported claim · first reported 3 Nov 2026 · 1 claim · best-carried claim: 2 separate publishers

    could not check

Walk the record from Colorectal Cancer

Open where it comes from, follow a claim or a related name, and use the trail to come back. Every step says what it is, how it stands and when. Machines read the same record.

Colorectal Cancer

Entity.

Evidence
2,119 documents · 430 separate publishers · a mention shows the name is in use, not that any claim about it is true
Standing
A name from our starting list; its record is kept up to date automatically from coverage
Time
first seen 11 Mar 2026, last seen 8 Nov 2026
Measured
6% of mentions say something specific about it; the rest only name it
As of
9 Nov 2026
18 links from here

Who it moves with: the 10 names are in the map above.

What is claimed about it (8)

  • Reported by two: Reported by two sources that did not copy each other.
  • Single source: Reported by one source so far.
  • Could not check: We could not count this claim's sources, so we do not say how well it is supported.

Situations it is named in (0)

none on file at this cutoff

For machines: this record as JSON

Watch this

What the coverage says

Recent reporting that names Colorectal Cancer, newest first. Open any row to follow it to the original article.

Evidence tiers: primary source = an official public record · attributed = a named outlet, receipt linked · lead = observed, not yet receipted.

What it connects to

Related records.

Recorded history

  • 9 Nov 2026

    coverage state changed: rising to steady

    Previous state held since 8 Nov 2026

  • 8 Nov 2026

    wire tier changed: watch to flagged

    Previous state held since 5 Nov 2026

  • 8 Nov 2026

    coverage state changed: insufficient_history to rising

    Previous state held since 5 Nov 2026

  • 5 Nov 2026

    wire tier changed: flagged to watch

    Previous state held since 4 Nov 2026

  • 5 Nov 2026

    coverage state changed: fading to insufficient_history

    Previous state held since 4 Nov 2026

  • 4 Nov 2026

    wire tier changed: watch to flagged

    Previous state held since 4 Nov 2026

  • 4 Nov 2026

    coverage state changed: insufficient_history to fading

    Previous state held since 4 Nov 2026

  • 4 Nov 2026

    wire tier changed: flagged to watch

    Previous state held since 28 Oct 2026

9 changes recorded since 3 Nov 2026; the newest 8 shown, newest first.

Ask about Colorectal CancerWatch Colorectal Cancer

Story momentum counts mentions in tracked coverage. Prices are the market’s own, cited with the venue. Informational only, not advice. As of 9 Nov 2026.